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AMINO ACIDS FOR MUSCLE RECOVERY AND PROTEIN SYNTHESIS
Amino Recover is a breakthrough product designed to use amino acids for muscle recovery and protein synthesis. There has been nearly 20 years of research conducted to arrive us at this very specific combination of amino acids in the most effective anabolic ratios. This formula is uniquely designed to support strength gain, function, and prevent muscle loss as a result of aging. Amino Recover offers you the right ratios to offer you the best results that essential amino acids have to offer.

Clinical Applications
Discussion
Suggested use: Dissolve one scoop (6.8 g) into 8-12 oz of room-temperature water and consume once per day between meals, or use as directed by your healthcare practitioner.
References:
1. Biolo G, Fleming RY, Maggi SP, et al. Transmembrane transport and intracellular kinetics of amino acids in human skeletal muscle. Am J Physiol. 1995 Jan;268(1 Pt 1):E75-84. [PMID: 7840186]
2. Volpi E, Ferrando AA, Yeckel CW, et al. Exogenous amino acids stimulate net muscle protein synthesis in the elderly. J Clin Invest. 1998 May 1;101(9):2000-07. [PMID: 9576765]
3. Tipton KD, Gurkin BE, Matin S, et al. Nonessential amino acids are not necessary to stimulate net muscle protein synthesis in healthy volunteers. J Nutr Biochem. 1999 Feb;10(2):89-95. [PMID: 15539275]
4. Volpi E, Mittendorfer B, Wolf SE, et al. Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction. Am J Physiol. 1999 Sep;277(3 Pt 1):E513-20. [PMID: 10484364]
5. Volpi E, Sheffield-Moore M, Rasmussen BB, et al. Basal muscle amino acid kinetics and protein synthesis in healthy young and older men. JAMA. 2001 Sep 12;286(10):1206- 12. [PMID: 11559266]
6. Tipton KD, Rasmussen BB, Miller SL, et al. Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. Am J Physiol Endocrinol Metab. 2001 Aug;281(2):E197-206. [PMID: 11440894]
7. Børsheim E, Tipton KD, Wolf SE, et al. Essential amino acids and muscle protein recovery from resistance exercise. Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E648-57. [PMID: 12217881]
8. Tipton KD, Børsheim E, Wolf SE, et al. Acute response of net muscle protein balance reflects 24-h balance after exercise and amino acid ingestion. Am J Physiol Endocrinol Metab. 2003 Jan;284(1):E76-89. [PMID: 12388164]
9. Volpi E, Kobayashi H, Sheffield-Moore M, et al. Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults. Am J Clin Nutr. 2003 Aug;78(2):250-58. [PMID: 12885705]
10. Paddon-Jones D, Sheffield-Moore M, Katsanos CS, et al. Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein. Exp Gerontol. 2006 Feb;41(2):215-59. [PMID: 16310330]
11. Paddon-Jones D, Sheffield-Moore M, Zhang XJ, et al. Amino acid ingestion improves muscle protein synthesis in the young and elderly. Am J Physiol Endocrinol Metab. 2004 Mar;286(3):E321-28. [PMID: 14583440]
12. Børsheim E, Aarsland A, Wolfe RR. Effect of an amino acid, protein, and carbohydrate mixture on net muscle protein balance after resistance exercise. Int J Sport Nutr Exerc Metab. 2004 Jun;14(3):255-71. [PMID: 15256687]
13. Katsanos CS, Kobayashi H, Sheffield-Moore M, et al. Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids. Am J Clin Nutr. 2005 Nov;82(5):1065-73. [PMID: 16280440]
14. Paddon-Jones D, Sheffield-Moore M, Urban RJ, et al. Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss in humans during 28 days bedrest. J Clin Endocrinol Metab. 2004 Sep;89(9):4351-58. [PMID: 15356032]
15. Katsanos CS, Kobayashi H, Sheffield-Moore M, et al. A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly. Am J Physiol Endocrinol Metab. 2006 Aug;291(2):E381-87. [PMID: 16507602]
16. Fitts RH, Romatowski JG, Peters JR, et al. The deleterious effects of bed rest on human skeletal muscle fibers are exacerbated by hypercortisolemia and ameliorated by dietary supplementation. Am J Physiol Cell Physiol. 2007 Jul;293(1):C313-20. [PMID: 17409123]
17. Børsheim E, Bui QU, Tissier S, et al. Effect of amino acid supplementation on muscle mass, strength and physical function in elderly. Clin Nutr. 2008 Apr;27(2):189-95. [PMID: 18294740]
18. Børsheim E, Bui QU, Tissier S, et al. Amino acid supplementation decreases plasma and liver triacylglycerols in elderly. Nutrition. 2009 Mar;25(3):281-88. [PMID: 19041223]
19. Katsanos CS, Aarsland A, Cree MG, et al. Muscle protein synthesis and balance responsiveness to essential amino acids ingestion in the presence of elevated plasma free fatty acid concentrations. J Clin Endocrinol Metab. 2009 Aug;94(8):2984-90. [PMID: 19454587]
20. Ferrando AA, Paddon-Jones D, Hays NP, et al. EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. Clin Nutr. 2010 Feb;29(1):18-23. [PMID: 19419806.]
21. Wolfe RR. Skeletal muscle protein metabolism and resistance exercise. J Nutr. 2006 Feb;136(2):525S-28S. [PMID: 16424140]
22. Ferrando A, Bamman M, Schutzler H, et al. Increased nitrogen intake following hip arthroplasty expedites muscle strength recovery. J Aging Res Clin Practice 2013;2(4):369-75. [on file]
23. Negro M, Giardina S, Marzani B, et al. Branched-chain amino acid supplementation does not enhance athletic performance but affects muscle recovery and the immune system. J Sports Med Phys Fitness. 2008 Sep;48(3):347-51. [PMID: 18974721]
24. Matsumoto K, Koba T, Hamada K, et al. Branched-chain amino acid supplementation attenuates muscle soreness, muscle damage and inflammation during an intensive training program. J Sports Med Phys Fitness. 2009 Dec;49(4):424-31. [PMID: 20087302] 25. Dickinson JM, Gundermann DM, Walker DK, et al. Leucine-enriched amino acid ingestion after resistance exercise prolongs myofibrillar protein synthesis and amino acid transporter expression in older men. J Nutr. 2014 Nov;144(11):1694-702. [PMID: 25332468]
https://www.ncbi.nlm.nih.gov/pubmed/26404370
https://www.ncbi.nlm.nih.gov/pubmed/25008857
https://www.ncbi.nlm.nih.gov/pubmed/24015935
Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.