Amino Recover

Amino Recover is a breakthrough product designed to use amino acids for muscle recovery and protein synthesis. There has been nearly 20 years of research conducted to arrive us at this very specific combination of amino acids in the most effective anabolic ratios. This formula is uniquely designed to support strength gain, function, and prevent muscle loss as a result of aging. Amino Recover offers you the right ratios to offer you the best results that essential amino acids have to offer.

Clinical Applications

Supports Muscular Strength and Optimal Functional

Supports Optimal Strength and Energy During the Workout

Offers Recovery Post Exercise

Supports Muscle Development In Both Young and Elderly

Discussion
The Amino Recover is a must have for building and maintaining strength. As an avid runner, weight lifter and cross-trained athlete, I am very active and need any edge I can to maintain strength. This amino acid formula has been studied by and developed by internationally recognized researchers in the field of muscle metabolism, anti-aging, and longevity. Seventeen years of research resulted in this particular blend of nine essential amino acids. This blend also includes but is not limited to branched chain amino acids such as leucine, isoleucine, valine, and arginine. They are proportioned in the most optimal ratios for muscle anabolism. Amino Recover is designed for both young and old who are seeking to stimulate muscle protein synthesis, quicken muscle recovery, and stimulate muscle strength and function.

Quality Over Quantity
Data shows that protein synthesis in both the young and elderly is primarily driven through essential amino acids. Studies demonstrate there is no benefit to protein synthesis from adding nonessential amino acids to an essential amino acid supplement. To give you an example, the addition of 22 g of non-essential AAs to 18 g of EAA offered no additional benefit to net muscle balance when compared to the provision of 18 g of EAAs alone. In addition, 15 g of EAA with ratios similar to Amino Recover, offered twice the impact on muscle protein synthesis than an equal amount of high quality protein.

Essential Amino Acids’ Effect on Exercise
Most people are familiar with taking EAAs post exercise; however the ingestion of EAAs prior to exercise increases delivery to the muscles in need. Research studies have demonstrated that exercise and amino acid intake has a positive effect on muscle protein synthesis. Branched chain amino acids have also improve post workout recovery time all while decreasing exercise induced muscle damage, promoting protein synthesis, and modulating exercise related cytokine production. For example, leucine enriched EAA supplementation extended the anabolic response and sensitivity of skeletal muscle to AAs. A study done by Borsheim et al says that over time, exercise will increase the beneficial effects of EAA supplementation on lean body mass, strength, muscle retention, and improve functional parameters of muscle.

Why Arginine?
Under normal demand in a healthy individual, arginine can be sufficiently synthesized. When an individual experiences increased stress, the arginine levels may not be met. There is also strong evidence that arginine has an effect on muscle growth and protein synthesis. Though the mechanisms as to how are not fully identified, it is likely multifactorial. It is known that arginine converts to nitrous oxide, which relaxes blood vessels and improves blood flow to muscles. One critical finding is that without arginine in the EAAs formula, plasma arginine decreases, potentially reducing the rate of protein synthesis.

Muscle Loss as a Result of Aging
When people think of EAAs, most direct their minds towards sports and athletics. What nobody is telling you is that there is incredible evidence that supports EAAs for aging. In the fourth decade of life, there is a natural catabolic effect or breakdown of muscle as a result of metabolic changes combined with sedentary lifestyle. Studies using EAAs at doses of 6.7 to 45 g/d in advanced age, bed rest, and recovery from surgery have shown important benefits. The benefits demonstrated increase in protein synthesis, enhanced muscle strength, and improvements in functional parameters of studied muscles. EAAs have huge potential in preserving muscle function in the elderly. Non-essential amino acids are not as effective as EAAs when it comes to muscle anabolism and may be inadequate to maximize anabolic efficiency in the elderly. High amounts of leucine as found in Amino Recover is also an important factor that is required for optimal stimulation of protein synthesis in the elderly. There is also research supported evidence that the presence of carbohydrates in a nutrition a supplement is not beneficial for the elderly and may impair muscle anabolism. Amino Recover is a highly effective blend of EAAs with arginine that provides zero carbohydrates.

Celarity Company Statement
Celarity Amino Recover is a state of the art products that is pharmaceutical grade and only to be sold by licensed practitioners. Celarity prides itself on being on the forefront of innovation in the natural health and holistic healing field. Celarity also prides itself on working with innovative doctors who are disruptors in the health care field.

Suggested use: Dissolve one scoop (6.8 g) into 8-12 oz of room-temperature water and consume once per day between meals, or use as directed by your healthcare practitioner.

References:
1. Biolo G, Fleming RY, Maggi SP, et al. Transmembrane transport and intracellular kinetics of amino acids in human skeletal muscle. Am J Physiol. 1995 Jan;268(1 Pt 1):E75-84. [PMID: 7840186]
2. Volpi E, Ferrando AA, Yeckel CW, et al. Exogenous amino acids stimulate net muscle protein synthesis in the elderly. J Clin Invest. 1998 May 1;101(9):2000-07. [PMID: 9576765]
3. Tipton KD, Gurkin BE, Matin S, et al. Nonessential amino acids are not necessary to stimulate net muscle protein synthesis in healthy volunteers. J Nutr Biochem. 1999 Feb;10(2):89-95. [PMID: 15539275]
4. Volpi E, Mittendorfer B, Wolf SE, et al. Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction. Am J Physiol. 1999 Sep;277(3 Pt 1):E513-20. [PMID: 10484364]
5. Volpi E, Sheffield-Moore M, Rasmussen BB, et al. Basal muscle amino acid kinetics and protein synthesis in healthy young and older men. JAMA. 2001 Sep 12;286(10):1206- 12. [PMID: 11559266]
6. Tipton KD, Rasmussen BB, Miller SL, et al. Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. Am J Physiol Endocrinol Metab. 2001 Aug;281(2):E197-206. [PMID: 11440894]
7. Børsheim E, Tipton KD, Wolf SE, et al. Essential amino acids and muscle protein recovery from resistance exercise. Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E648-57. [PMID: 12217881]
8. Tipton KD, Børsheim E, Wolf SE, et al. Acute response of net muscle protein balance reflects 24-h balance after exercise and amino acid ingestion. Am J Physiol Endocrinol Metab. 2003 Jan;284(1):E76-89. [PMID: 12388164]
9. Volpi E, Kobayashi H, Sheffield-Moore M, et al. Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults. Am J Clin Nutr. 2003 Aug;78(2):250-58. [PMID: 12885705]
10. Paddon-Jones D, Sheffield-Moore M, Katsanos CS, et al. Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein. Exp Gerontol. 2006 Feb;41(2):215-59. [PMID: 16310330]
11. Paddon-Jones D, Sheffield-Moore M, Zhang XJ, et al. Amino acid ingestion improves muscle protein synthesis in the young and elderly. Am J Physiol Endocrinol Metab. 2004 Mar;286(3):E321-28. [PMID: 14583440]
12. Børsheim E, Aarsland A, Wolfe RR. Effect of an amino acid, protein, and carbohydrate mixture on net muscle protein balance after resistance exercise. Int J Sport Nutr Exerc Metab. 2004 Jun;14(3):255-71. [PMID: 15256687]
13. Katsanos CS, Kobayashi H, Sheffield-Moore M, et al. Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids. Am J Clin Nutr. 2005 Nov;82(5):1065-73. [PMID: 16280440]
14. Paddon-Jones D, Sheffield-Moore M, Urban RJ, et al. Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss in humans during 28 days bedrest. J Clin Endocrinol Metab. 2004 Sep;89(9):4351-58. [PMID: 15356032]
15. Katsanos CS, Kobayashi H, Sheffield-Moore M, et al. A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly. Am J Physiol Endocrinol Metab. 2006 Aug;291(2):E381-87. [PMID: 16507602]
16. Fitts RH, Romatowski JG, Peters JR, et al. The deleterious effects of bed rest on human skeletal muscle fibers are exacerbated by hypercortisolemia and ameliorated by dietary supplementation. Am J Physiol Cell Physiol. 2007 Jul;293(1):C313-20. [PMID: 17409123]
17. Børsheim E, Bui QU, Tissier S, et al. Effect of amino acid supplementation on muscle mass, strength and physical function in elderly. Clin Nutr. 2008 Apr;27(2):189-95. [PMID: 18294740]
18. Børsheim E, Bui QU, Tissier S, et al. Amino acid supplementation decreases plasma and liver triacylglycerols in elderly. Nutrition. 2009 Mar;25(3):281-88. [PMID: 19041223]
19. Katsanos CS, Aarsland A, Cree MG, et al. Muscle protein synthesis and balance responsiveness to essential amino acids ingestion in the presence of elevated plasma free fatty acid concentrations. J Clin Endocrinol Metab. 2009 Aug;94(8):2984-90. [PMID: 19454587]
20. Ferrando AA, Paddon-Jones D, Hays NP, et al. EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. Clin Nutr. 2010 Feb;29(1):18-23. [PMID: 19419806.]
21. Wolfe RR. Skeletal muscle protein metabolism and resistance exercise. J Nutr. 2006 Feb;136(2):525S-28S. [PMID: 16424140]
22. Ferrando A, Bamman M, Schutzler H, et al. Increased nitrogen intake following hip arthroplasty expedites muscle strength recovery. J Aging Res Clin Practice 2013;2(4):369-75. [on file]
23. Negro M, Giardina S, Marzani B, et al. Branched-chain amino acid supplementation does not enhance athletic performance but affects muscle recovery and the immune system. J Sports Med Phys Fitness. 2008 Sep;48(3):347-51. [PMID: 18974721]
24. Matsumoto K, Koba T, Hamada K, et al. Branched-chain amino acid supplementation attenuates muscle soreness, muscle damage and inflammation during an intensive training program. J Sports Med Phys Fitness. 2009 Dec;49(4):424-31. [PMID: 20087302] 25. Dickinson JM, Gundermann DM, Walker DK, et al. Leucine-enriched amino acid ingestion after resistance exercise prolongs myofibrillar protein synthesis and amino acid transporter expression in older men. J Nutr. 2014 Nov;144(11):1694-702. [PMID: 25332468]


https://www.ncbi.nlm.nih.gov/pubmed/26404370
https://www.ncbi.nlm.nih.gov/pubmed/25008857
https://www.ncbi.nlm.nih.gov/pubmed/24015935

Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.